Science-科学杂志2023.12.15期下载电子版PDF网盘订阅

本期封面：科学杂志的 “2023 年年度突破 “聚焦正在重塑医学和流行文化的 GLP-1 激动剂药物。今年的研究表明，除了能让数百万人减轻体重外，这些药物还可能对包括心力衰竭和肾病在内的各种疾病有显著疗效。然而，人们对这些药物的热情也引发了一些棘手的问题，如公平性和肥胖症的持续耻辱化。
Science’s 2023 Breakthrough of the Year spotlights the GLP-1 agonist drugs that are reshaping medicine and popular culture. Studies this year suggest that besides enabling millions of people to shed weight, they may have compelling benefits for medical conditions, including heart failure and kidney disease. However, enthusiasm for the drugs also raises difficult questions about equity and the continuing stigma of obesity.